When designing channels for a polysulfone product, double-sided full round or single-sided D-channels are possible. Full round channels give the best flow and the least opportunity for unswept volume. The typical minimal channel size is 0.020 (0.5 mm) for polysulfone with channel spacing a preferred 1x apart. Tighter spacing is possible in low-pressure applications.
Unlimited layers are theoretically possible with polysulfone, but costs rise exponentially with layer count. In practice, multiple two-layer manifolds are a smarter choice than a single large, highly complex three-or-more-layer one. While general performance is higher with polysulfone than with acrylic and polycarbonate, it is more expensive from a raw material perspective.
When building polysulfone products, use threaded inserts only when frequent assembly/disassembly is expected. Directly threaded polysulfone fluidic manifolds will perform acceptably for single-assembly applications (if torque limits are not exceeded at the time of installation). Staked-in threaded inserts are recommended over helicoils when using polysulfone to avoid stress-cracking concerns.