The connection type choices depend on a few factors. These include the style of tubing, expected lifecycle of tubing, cost, and use-case. In medical and life science applications, often the tubing style is the most critical factor that dictates the connection type. For example, if thick-walled flexible tubing is required a barb-style fitting will be best. In contrast, if thin-walled highly chemically inert connections are required, one might choose flared tubing and connection type to ensure there is the lowest possibility of carry-over or fluidic contact with a metal ferrule.
Typically flared, or sometimes referred to as flanged, most consider these kinds of tubing assemblies more cost efficient as they have a less expensive component, i.e. the O-ring/washer vs ferrule. However, this means that the tubing length cannot be adjusted as easily because the O-ring and fitting are installed prior to cutting and flaring the tubing. When using a ferruled connection, users can cut and recut the tubing as needed with the ferrule plus fitting installed without specialized equipment to create a tubing flare.
Ferrules tubing assemblies, or often referred to as flangeless, provide some benefits and drawbacks as well. Ferrules are easier to replace as special tools to create a flare are not required. They are also “free-spinning”, which can reduce strain on tubing depending on the application.
Just as the type of connection is critical, same is true for the fitting material. Standard options are Polypropylene (lower cost), PEEK (most resistant to wear), and PVDF (less constrictive than PEEK).
We recommend that designers also consider another mechanism in which the fitting is installed in the manifold and “head style”. These can be finger-tight, headless, hex head, or torque-limiting. Below are some visual examples.